Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427033 | 0.88 | MAPK1 (0.60) | AKR1C3TP53MAPTKMT2AMEN1 | |
| SCHEMBL425498 | 0.79 | FAAH (0.58) | AKR1C3MAPTKMT2ALMNAMEN1 | |
| SCHEMBL425711 | 0.78 | AKR1C3 (0.49) | AKR1C3MAPT | |
| SCHEMBL424468 | 0.78 | MAP4K1 (0.42) | AKR1C3MAPTKMT2AMEN1 | |
| SCHEMBL27607283 | 0.72 | AKR1C3 (0.83) | AKR1C3KMT2ALMNAMEN1SLC6A7 | |
| SCHEMBL426884 | 0.71 | PARP10 (0.56) | AKR1C3TP53MAPTKMT2ALMNA | |
| SCHEMBL15127495 | 0.71 | MAPT (0.63) | TP53MAPTKMT2ALMNAMEN1 | |
| SCHEMBL427358 | 0.70 | DGAT1 (0.50) | AKR1C3MAPTLMNAHTT | |
| SCHEMBL426876 | 0.70 | POLB (0.44) | TP53MAPTKMT2ALMNAMEN1 | |
| SCHEMBL28483179 | 0.69 | GFER (0.52) | TP53MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |