Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896420 | 0.77 | KDM1A (0.40) | KDM1AADORA3ABCB1 | |
| SCHEMBL7896392 | 0.75 | POLB (0.33) | LMNARAB9A | |
| SCHEMBL13085024 | 0.61 | NPSR1 (0.46) | TP53LMNATSHRMAPK1HSD17B10 | |
| SCHEMBL6551088 | 0.61 | LMNA (0.46) | KDM1ATP53LMNATSHRMAPK1 | |
| SCHEMBL7902694 | 0.60 | MAPK1 (0.34) | MAPK1HSD17B10 | |
| SCHEMBL11779560 | 0.59 | RAB9A (0.47) | KDM1ATP53LMNATSHRMAPK1 | |
| SCHEMBL7896518 | 0.58 | POLB (0.42) | LMNAMAPK1HSD17B10 | |
| SCHEMBL8118093 | 0.58 | GAA (0.46) | KDM1ATP53LMNATSHRMAPK1 | |
| SCHEMBL6680308 | 0.57 | GAA (0.49) | KDM1ATP53LMNATSHRMAPK1 | |
| SCHEMBL27871624 | 0.57 | LMNA (0.43) | KDM1ATP53LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |