Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 4/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900088 | 0.88 | HPGD (0.46) | ITGB3ITGA2BGAAITGAVTAS1R3 | |
| SCHEMBL7892878 | 0.87 | FOLH1 (0.47) | ITGB3ITGA2BGAAITGAVTAS1R3 | |
| SCHEMBL7904023 | 0.87 | GAA (0.42) | ITGB3ITGA2BGAAITGAVTAS1R3 | |
| SCHEMBL7898913 | 0.85 | GAA (0.42) | ITGB3ITGA2BGAAF2RITGAV | |
| SCHEMBL7900090 | 0.83 | GAA (0.41) | ITGB3ITGA2BGAAITGAVTAS1R3 | |
| SCHEMBL4701718 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BGAAF2RITGAV | |
| SCHEMBL4702523 | 0.82 | GAA (0.48) | ITGB3ITGA2BGAAF2RITGAV | |
| SCHEMBL7892930 | 0.81 | KMT2A (0.44) | ITGB3GAAITGAVTAS1R3TAS1R1 | |
| SCHEMBL4699864 | 0.81 | MAPT (0.44) | ITGB3ITGA2BGAAITGAVTAS1R3 | |
| SCHEMBL7898800 | 0.80 | GAA (0.41) | ITGB3ITGA2BGAAF2RITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |