SCHEMBL7904061

SCHEMBL7904061

C=C(OCc1ccccc1)c1cccc(CCl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.50
KMT2A Q03164 3/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ALDH1A1 P00352 8/20 0.43
RAB9A P51151 5/20 0.43
LMNA P02545 4/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.40
NR4A2 P43354 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
MAPK1 P28482 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900447 0.85 KMT2A (0.47) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL7900091 0.83 KMT2A (0.49) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL5367985 0.82 TDP1 (0.59) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL318600 0.82 TDP1 (0.71) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL7892900 0.80 ALDH1A1 (0.65) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL7901728 0.79 PRSS1 (0.46) TDP1KMT2ASLC6A2SLC6A3RAB9A
SCHEMBL7901936 0.78 MAOB (0.55) KMT2ARAB9ANPC1SMN1; SMN2NR4A2
SCHEMBL28196657 0.78 TDP1 (0.53) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL8581235 0.76 RAB9A (0.74) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL7900095 0.75 SMN1; SMN2 (0.38) TDP1KMT2ASLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197905-B1 VINYL ETHER CHAIN TRANSFER AGENT TERMINATES THE GROWTH OF THE POLYMER CHAIN BY ADDITION TO THE PROPAGATING POLYMER RADICAL FOLLOWED BY EXPULSION OF A RADICAL WHICH THEN INITIATES ANOTHER POLYMER CHAIN COMMONWEALTH SCIENTIFIC & INDUSTRIAL RESARCH ORGANIZATION (AU) 2001-03-06 US disclosed
US-5932675-A Free-radical chain transfer polymerization process COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-08-03 US disclosed
US-5874511-A CHAIN TRANSFER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-23 US disclosed
EP-0333758-B1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS COMMW SCIENT IND RES ORG (AU) 1995-11-02 EP disclosed
US-5385996-A Control of molecular weight and end-group functionality of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1995-01-31 US disclosed
EP-0333758-A4 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1990-05-14 EP disclosed
EP-0333758-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1989-09-27 EP disclosed
WO-1988004304-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1988-06-16 WO disclosed