Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776766 | 0.99 | HRH1 (0.60) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL14524946 | 0.94 | HRH1 (0.61) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL31243785 | 0.88 | CNR1 (0.70) | SIGMAR1HRH1HRH3CNR1 | |
| SCHEMBL7775266 | 0.86 | NPC1 (0.52) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL7775252 | 0.85 | HRH1 (0.56) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL9697267 | 0.84 | POLB (0.56) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL14560427 | 0.83 | FAAH (0.78) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL31391950 | 0.82 | CNR1 (0.54) | SIGMAR1HRH1HRH3POLBTDP1 | |
| SCHEMBL31318279 | 0.82 | CNR1 (0.73) | HRH1HRH3POLBTDP1CNR1 | |
| SCHEMBL7773267 | 0.81 | NPC1 (0.55) | SIGMAR1HRH1HRH3POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242268-B1 | USING WATER-SOLUBLE, FLUORESCENT, RARE EARTH METAL CHELATES AS TAGS ON SPECIFIC BINDING PARTNERS AND DETECTING FLUORESCENT EMISSION FROM SAMPLE AFTER FLUORESCENCE OF AMBIENT SUSBTANCES HAVE DECAYED | EG&G WALLAC (FI) | 2001-06-05 | — | — | US | disclosed |
| US-5830769-A | QUANTITATIVE ANALYSIS; MEASURING FLUORESCENT EMISSION | PERKINELMER LIFE SCIENCES, INC. | 1998-11-03 | — | — | US | disclosed |
| EP-0272320-B1 | HOMOGENEOUS FLUOROASSAY METHODS EMPLOYING FLUORESCENT BACKGROUND REJECTION | BAXTER DIAGNOSTICS INC (US) | 1994-03-23 | — | — | EP | disclosed |