Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.78 |
| ▸ | CNR1 | P21554 | 3/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723082 | 0.94 | CNR1 (0.74) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL20290801 | 0.93 | CNR1 (0.70) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL20290800 | 0.93 | CNR1 (0.70) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL20290109 | 0.93 | CNR1 (0.70) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL11885815 | 0.88 | POLB (0.63) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL14104950 | 0.86 | FAAH (0.70) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL11421096 | 0.84 | HRH1 (0.63) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL10754550 | 0.84 | HRH1 (0.63) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL14560430 | 0.83 | CNR1 (0.60) | FAAHCNR1SIGMAR1HRH1HRH3 | |
| SCHEMBL7904117 | 0.83 | SIGMAR1 (0.60) | FAAHCNR1SIGMAR1HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |