Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400200 | 0.90 | TSHR (0.47) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL4467924 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL22877649 | 0.85 | SCN1A (0.36) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL24292366 | 0.83 | CHRM2 (0.40) | LMNATSHRCHRM1 | |
| SCHEMBL24292365 | 0.82 | CHRM2 (0.35) | ALDH1A1CHRM1HPGD | |
| SCHEMBL24292367 | 0.82 | CHRM1 (0.46) | LMNATSHRCHRM1L3MBTL1MAPK1 | |
| SCHEMBL24292292 | 0.78 | CHRM2 (0.33) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL18534232 | 0.77 | — | — | |
| SCHEMBL896075 | 0.76 | CHRM3 (0.39) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL47935 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | disclosed |
| US-4946654-A | PRESET, UNIFORM GRAIN SIZE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | disclosed |
| US-4924025-A | HEAT RESISTANT POLYMER MONOMERS, BIS/P-HYDROXYBENZOATE OF HYDROGENATED BISPHENOL A | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4150106-A | Toothpaste permitting of controlling the tooth brushing time | COOPER S.A. (CH) | 1979-04-17 | — | — | US | disclosed |