Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598039 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LMNAESR1TSHRTDP1 | |
| SCHEMBL521940 | 0.90 | ESR1 (0.46) | ALDH1A1LMNAESR1TSHRTDP1 | |
| SCHEMBL3110549 | 0.90 | SERPINE1 (0.37) | TSHRTDP1 | |
| SCHEMBL9312179 | 0.88 | ALDH1A1 (0.49) | ALDH1A1LMNAESR1TSHRKDM4E | |
| SCHEMBL659382 | 0.88 | ALDH1A1 (0.49) | ALDH1A1LMNAESR1TSHRKDM4E | |
| SCHEMBL190524 | 0.88 | ALDH1A1 (0.49) | ALDH1A1LMNAESR1TSHRKDM4E | |
| SCHEMBL1435298 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1KDM4E | |
| SCHEMBL48012 | 0.77 | LMNA (0.37) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL19304541 | 0.76 | PRSS1 (0.49) | ALDH1A1LMNAESR1TSHRTDP1 | |
| SCHEMBL2355854 | 0.75 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3520791-A1 | NIFEDIPINE-BASED COMPOSITION FOR THE USE IN THE TREATMENT OF ANAL FISSURES AND PROCTALGYA, AND METHOD FOR ADMINISTRATION THEREOF | Antropoli, Carmine (IT) | 2019-08-07 | — | — | EP | claimed |
| EP-2393552-B1 | A CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2017-12-20 | — | — | EP | claimed |
| US-9708292-B2 | Cyanopyrimidine derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-18 | — | — | US | claimed |
| EP-2253304-B1 | Nifedipine-based compositions for anti-wrinkle treatments | ANTROPOLI CARMINE (IT) | 2015-11-11 | — | — | EP | claimed |
| US-20120022077-A1 | NOVEL CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-26 | — | — | US | claimed |
| EP-2393552-A1 | A NOVEL CYANOPYRIMIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | claimed |
| EP-2253304-A2 | Nifedipine-based compositions for anti-wrinkle treatments | Antropoli, Carmine (IT) | 2010-11-24 | — | — | EP | claimed |
| WO-2010090299-A1 | A NOVEL CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-12 | — | — | WO | claimed |
| EP-1558227-B1 | INJECTABLE 2,6-DIISOPROPYLPHENOL-CONTAINING ANESTHETIC COMPOSITION AND METHODS | DAEWON PHARM CO LTD (KR) | 2006-10-04 | — | — | EP | claimed |
| EP-1558227-A1 | INJECTABLE 2,6-DIISOPROPYLPHENOL-CONTAINING ANESTHETIC COMPOSITION AND METHODS | Centurion, Inc. (KR) | 2005-08-03 | — | — | EP | claimed |
| US-20040067919-A1 | Injectable 2, 6-diisopropylphenol-containing anesthetic composition and methods | CENTURION INC. | 2004-04-08 | — | — | US | claimed |
| US-5637304-A | Cosmetical or pharmaceutical compositions comprising deacylated glycerophospholipids for topical use | FLARER S.A. PHARMACEUTICAL FINE CHEMICALS (CH) | 1997-06-10 | — | — | US | claimed |
| US-5575994-A | AGING RESISTANCE AND STORAGE STABILITY OF MIXTURES USING BACTERIOSTATS AND ANTIMICOTICS | ISTITUTO GENTILI S.P.A. (IT) | 1996-11-19 | — | — | US | claimed |
| EP-0613367-B1 | DERMATOLOGICAL AND COSMETIC COMPOSITIONS | GENTILI IST SPA (IT) | 1995-11-02 | — | — | EP | claimed |
| EP-0613367-A1 | DERMATOLOGICAL AND COSMETIC COMPOSITIONS. | GENTILI IST SPA (IT) | 1994-09-07 | — | — | EP | claimed |
| US-5300293-A | Mixture of antigrowth agent and dextrin | SUMITOMO CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | claimed |
| WO-1993009760-A2 | DERMATOLOGICAL AND COSMETIC COMPOSITIONS | ISTITUTO GENTILI S.P.A. (IT) | 1993-05-27 | — | — | WO | claimed |
| US-5096710-A | Cockroaches, juvenile hormone or chitin synthesis inhibitor, dextrin, plant oil | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-17 | — | — | US | claimed |
| US-4985413-A | Poison bait for control of noxious insects | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | claimed |
| US-4834977-A | Poison bait for control of noxious insects | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022077-A1 | NOVEL CYANOPYRIMIDINE DERIVATIVE | ADORA2A, ADORA1, ADORA3 | ALDH1A1 1232/4885LMNA 4003/4885ESR1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.