Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 7/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790824 | 0.86 | ALPL (0.56) | ALPLPIK3CGSLC40A1PIK3CDPIK3CA | |
| SCHEMBL29556839 | 0.86 | ALPL (0.56) | ALPLPIK3CGSLC40A1PIK3CDPIK3CA | |
| SCHEMBL29556249 | 0.84 | ALPL (0.52) | ALPLGLO1BRAFPIK3CGSLC40A1 | |
| SCHEMBL791102 | 0.84 | ALPL (0.52) | ALPLGLO1BRAFPIK3CGSLC40A1 | |
| SCHEMBL28554047 | 0.83 | ALPL (0.51) | ALPLPIK3CGSLC40A1PIK3CDPIK3CA | |
| SCHEMBL29555742 | 0.82 | ALPL (0.58) | ALPLBRAFPIK3CGSLC22A12PIK3CD | |
| SCHEMBL30333038 | 0.82 | ALPL (0.58) | ALPLBRAFPIK3CGSLC22A12PIK3CD | |
| SCHEMBL15560224 | 0.82 | ALPL (0.58) | ALPLBRAFPIK3CGSLC22A12PIK3CD | |
| SCHEMBL791091 | 0.81 | ALPL (0.57) | ALPLSLC40A1 | |
| SCHEMBL15459551 | 0.81 | ALPL (0.52) | ALPLPIK3CGSLC40A1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |