Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904425 | 1.00 | PRCP (0.36) | PRCPSIGMAR1 | |
| SCHEMBL7904422 | 1.00 | PRCP (0.36) | PRCPSIGMAR1 | |
| SCHEMBL7902289 | 1.00 | PRCP (0.36) | PRCPSIGMAR1 | |
| SCHEMBL7902288 | 1.00 | PRCP (0.36) | PRCPSIGMAR1 | |
| SCHEMBL7904440 | 0.83 | — | — | |
| SCHEMBL7904443 | 0.83 | — | — | |
| SCHEMBL7902256 | 0.82 | CYP1A2 (0.35) | PRCP | |
| SCHEMBL7902097 | 0.80 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL7903491 | 0.74 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL9387637 | 0.68 | HTR1A (0.39) | PRCPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201119-B1 | 2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-9-AMINE COMPOUNDS USEFUL AS INTERMEDIATES TO ANTIVIRALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-03-13 | — | — | US | disclosed |
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | disclosed |
| US-5270464-A | Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-14 | — | — | US | disclosed |