Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5167421 | 0.92 | TSHR (0.37) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL2332407 | 0.87 | — | — | |
| Methyl Phosphonate SCHEMBL28215606 | 0.82 | CA2 (0.42) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL3015655 | 0.82 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL3014553 | 0.78 | PAOX (0.39) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL29789433 | 0.78 | TSHR (0.37) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL3012810 | 0.78 | TSHR (0.37) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL3123373 | 0.76 | S1PR2 (0.39) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Phosphoric Acid SCHEMBL3008673 | 0.76 | S1PR2 (0.39) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Formic Acid SCHEMBL20943376 | 0.75 | TSHR (0.40) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586066-B2 | Topical antifungal composition | DELCOR ASSET CORPORATION (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120070384-A1 | TOPICAL ANTIFUNGAL COMPOSITION | STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) | 2012-03-22 | — | — | US | disclosed |
| US-20110251146-A1 | TOPICAL ANTIFUNGAL COMPOSITION | STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) | 2011-10-13 | — | — | US | disclosed |
| US-8026238-B2 | Topical antifungal composition | Stiefel Research Australia, Pty Ltd (AU) | 2011-09-27 | — | — | US | disclosed |
| US-7553835-B1 | Topical antifungal composition | STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) | 2009-06-30 | — | — | US | disclosed |
| US-20090149473-A1 | Topical antifungal composition | STIEFEL RESEARCH AUSTRALIA PTY LTD. (AU) | 2009-06-11 | — | — | US | disclosed |
| EP-1024792-B1 | TOPICAL ANTIFUNGAL COMPOSITION | CONNETICS AUSTRALIA PTY LTD (AU) | 2006-11-29 | — | — | EP | disclosed |
| EP-1692951-A1 | Topical antifungal composition | Connetics Australia Pty Limited (AU) | 2006-08-23 | — | — | EP | disclosed |
| EP-1024792-A4 | TOPICAL ANTIFUNGAL COMPOSITION | SOLTEC RES PTY LTD (AU) | 2001-08-08 | — | — | EP | disclosed |
| EP-1024792-A1 | TOPICAL ANTIFUNGAL COMPOSITION | SOLTEC RESEARCH PTY. LTD. (AU) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020250-A1 | TOPICAL ANTIFUNGAL COMPOSITION | SOLTEC RESEARCH PTY. LTD. (AU) | 1999-04-29 | — | — | WO | disclosed |
| US-5612024-A | SHAMPOO | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-03-18 | — | — | US | disclosed |
| US-4831197-A | USING CATION EXCHANGE CATALYST AND SURFACTANT | DEUTSCHE TEXACO AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0191236-A1 | Insecticidal compositions | ATARON DEVELOPMENT (1985) LTD. (IL) | 1986-08-20 | — | — | EP | disclosed |
| US-4575476-A | SURGEON'S GLOVES | Podell, Howard I. (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0002127-A1 | Shaving composition | Moss, Arthur (GB) | 1979-05-30 | — | — | EP | disclosed |