Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19797419 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL30682640 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL26931387 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL26931581 | 0.79 | FDPS (0.46) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL30682681 | 0.79 | FDPS (0.46) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL30682781 | 0.77 | FDPS (0.38) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL30682656 | 0.77 | GBA1 (0.43) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL26931522 | 0.77 | GBA1 (0.43) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL26931487 | 0.77 | FDPS (0.38) | KDM4EALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL26931664 | 0.76 | GBA1 (0.42) | KDM4EALDH1A1FDPSNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281303-B1 | TRANSITION METAL COMPLEX | EASTMAN CHEMICAL COMPANY | 2001-08-28 | — | — | US | disclosed |