Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906895 | 1.00 | CA12 (0.46) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL12204994 | 0.98 | CA12 (0.47) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL7905907 | 0.94 | ALDH1A1 (0.45) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL19753862 | 0.92 | CA12 (0.43) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL18613994 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL18644929 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL881292 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL4379133 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL478342 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 | |
| SCHEMBL1145153 | 0.90 | ALDH1A1 (0.53) | CA12CA1CA9ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780644-A | BRANCHES AND CASCADES OF POLYOXYALKYLENE GLYCOLS; DRUG CARRIERS; CONTRAST AGENTS FOR MEDICAL IMAGING | DIBRA S.P.A. (IT) | 1998-07-14 | — | — | US | claimed |
| EP-0750649-B1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO IMAGING SPA (IT) | 2001-12-19 | — | — | EP | disclosed |
| US-5886110-A | LESS COMPACT STRUCTURES TO AVOID FUNCTIONAL GROUP CROWDING ON THE SURFACE; A CENTRAL NUCLEUS OR ?CORE? WITH RADIATING CHAINS | DIBRA S.P.A. (IT) | 1999-03-23 | — | — | US | disclosed |
| US-5780644-A | BRANCHES AND CASCADES OF POLYOXYALKYLENE GLYCOLS; DRUG CARRIERS; CONTRAST AGENTS FOR MEDICAL IMAGING | DIBRA S.P.A. (IT) | 1998-07-14 | — | — | US | disclosed |
| EP-0750649-A1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO S.p.A. (IT) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025763-A1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO S.P.A. (IT) | 1995-09-28 | — | — | WO | disclosed |