Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644929 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL18613994 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL12865316 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL4379133 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL881292 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL922407 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL478342 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL241884 | 0.94 | CA1 (0.52) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL25398474 | 0.93 | ALDH1A1 (0.47) | ALDH1A1CA1CA9CA12GAA | |
| SCHEMBL1218220 | 0.93 | ALDH1A1 (0.47) | ALDH1A1CA1CA9CA12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290412-A | Glutamate dehydrogenase degradation agent and preparation method and application thereof | 杭州汉菁生物科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-116003378-B | PD-L1 targeted molecular probe and application thereof | 江苏省原子医学研究所 | 2024-03-12 | — | — | CN | claimed |
| CN-116003378-A | PD-L1 targeted molecular probe and application thereof | 江苏省原子医学研究所 | 2023-04-25 | — | — | CN | claimed |
| CN-113354956-B | Near-infrared squaric acid dye connected with oxygen ether chain as well as preparation and application thereof | 福州大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114292296-A | Preparation method of anti-mud factor and anti-mud polycarboxylate superplasticizer | 湖州绿色新材股份有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-112409596-A | Polysulfone and preparation method thereof | 万华化学集团股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| US-20260116867-A1 | PROTEOLYSIS TARGETING CHIMERAS FOR HUMAN PREGNANE X RECEPTOR AND FOR DEGRADATION OF GSPT1 | ST JUDE CHILDRENS RES HOSPITAL (US) | 2026-04-30 | — | — | US | disclosed |
| US-12594264-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-12590111-B2 | Flavonoid derivative for treating dental caries | MÜHLBAUER TECHNOLOGY GMBH (DE) | 2026-03-31 | — | — | US | disclosed |
| EP-3852767-B1 | CALCIUM OXALATE CRYSTALLIZATION INHIBITORS FOR RENAL DISORDERS | VIFOR INT AG (CH) | 2025-12-17 | — | — | EP | disclosed |
| US-12377152-B2 | Compounds for degrading alpha-synuclein aggregates and uses thereof | APRINOIA THERAPEUTICS LIMITED (CN) | 2025-08-05 | — | — | US | disclosed |
| US-20250228944-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS | ARVINAS OPERATIONS, INC. | 2025-07-17 | — | — | US | disclosed |
| EP-4467631-B1 | MIXTURE COMPRISING EUROPIUM-ORGANIC COORDINATION COMPOUND AND METHOD FOR PRODUCING THE SAME | BEEOLED GMBH (DE) | 2025-05-14 | — | — | EP | disclosed |
| EP-0494925-A1 | POLYMERIZABLE (FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1992-07-22 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5028721-A | Bis(functionally-substituted phenylene) semi-rigid crowns and process for making | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1991-07-02 | — | — | US | disclosed |
| WO-1991004971-A1 | POLYMERIZABLE (FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| EP-0341409-A1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590111-B2 | Flavonoid derivative for treating dental caries | ITGA8, ICAM1, ITGA2 | ALDH1A1 1402/4885CA1 1169/4885CA9 2320/4885 |
| US-12377152-B2 | Compounds for degrading alpha-synuclein aggregates and uses thereof | SNCA, PARK7, PRNP | ALDH1A1 2065/4885CA1 3596/4885CA9 4039/4885 |
| US-12594264-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | ADRM1, CRBN, SNCA | ALDH1A1 3149/4885CA1 3727/4885CA9 4838/4885 |
| US-20250228944-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS | BRPF3, STUB1, BRDT | ALDH1A1 3365/4885CA1 2626/4885CA9 3703/4885 |
| US-20260116867-A1 | PROTEOLYSIS TARGETING CHIMERAS FOR HUMAN PREGNANE X RECEPTOR AND FOR DEGRADATION OF GSPT1 | NR3C1, GPER1, NR1H4 | ALDH1A1 3595/4885CA1 932/4885CA9 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.