Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904730 | 0.85 | FLT3 (0.40) | HSD17B10KDM4ELMNAL3MBTL1CYP1A2 | |
| SCHEMBL7905726 | 0.85 | FLT3 (0.40) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TDP1 | |
| SCHEMBL7902622 | 0.85 | KDM4E (0.36) | ALDH1A1HSD17B10KDM4ELMNAMEN1 | |
| SCHEMBL7896441 | 0.84 | HTR1B (0.37) | ALDH1A1KDM4EHTR1B | |
| SCHEMBL7903994 | 0.81 | ATP4A (0.40) | — | |
| SCHEMBL7904663 | 0.80 | MEN1 (0.35) | ALDH1A1HTTKDM4ELMNAL3MBTL1 | |
| SCHEMBL7896411 | 0.79 | USP2 (0.43) | ALDH1A1KDM4ELMNAL3MBTL1CYP1A2 | |
| SCHEMBL7896426 | 0.76 | MAPK1 (0.42) | ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL7903985 | 0.75 | KDM4E (0.34) | ALDH1A1HSD17B10SMN1; SMN2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7905880 | 0.75 | KDM4E (0.32) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |