Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896514 | 0.93 | HRH3 (0.42) | MEN1KMT2AHRH3KCNH2BACE1 | |
| SCHEMBL7908450 | 0.92 | HRH3 (0.43) | MEN1KMT2AHRH3KCNH2BACE1 | |
| SCHEMBL7896411 | 0.91 | USP2 (0.43) | HRH3KCNH2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7905726 | 0.85 | FLT3 (0.40) | ALDH1A1L3MBTL1KDM4EFLT3POLB | |
| SCHEMBL7902622 | 0.85 | KDM4E (0.36) | MEN1KMT2AHRH3ALDH1A1KDM4E | |
| SCHEMBL7904450 | 0.84 | FLT3 (0.40) | ALDH1A1L3MBTL1KDM4EFLT3POLB | |
| SCHEMBL7904730 | 0.83 | FLT3 (0.40) | BACE1L3MBTL1KDM4ECYP2D6FLT3 | |
| SCHEMBL7896441 | 0.83 | HTR1B (0.37) | HRH3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7903914 | 0.82 | HTR1B (0.36) | HRH3ALDH1A1KDM4E | |
| SCHEMBL7908577 | 0.82 | FLT3 (0.39) | BACE1L3MBTL1KDM4ECYP2D6FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |