Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996701 | 0.86 | SRD5A2 (0.50) | SRD5A2SRD5A1SHBGAR | |
| SCHEMBL8084448 | 0.72 | SRD5A2 (0.52) | SRD5A2SRD5A1SHBGAR | |
| SCHEMBL8084449 | 0.72 | SRD5A2 (0.52) | SRD5A2SRD5A1SHBGAR | |
| SCHEMBL8016963 | 0.72 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL7380929 | 0.72 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8016669 | 0.72 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL7386216 | 0.72 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8016958 | 0.72 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL7382151 | 0.71 | SRD5A2 (0.71) | SRD5A2SRD5A1SHBG | |
| SCHEMBL7383910 | 0.71 | SRD5A2 (0.57) | SRD5A2SRD5A1SHBGAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204273-B1 | TREATMENT OF ANDROGENIC SENSITIVE DISORDERS SUCH AS ACNE VULGARIS, SEBORRHEA, FEMALE HIRSUTISM, MALE PATTERN BALDNESS, AND BENIGN PROSTATIC HYPERPLASIA. | MERCK & CO., INC. | 2001-03-20 | — | — | US | disclosed |