Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 4/20 | 0.35 |
| ▸ | FNTB | P49356 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906933 | 0.91 | LTB4R2 (0.42) | IDO1LTB4R2ADRB1ADRB3 | |
| SCHEMBL7907018 | 0.89 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7905224 | 0.85 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7906339 | 0.84 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7906347 | 0.84 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7907130 | 0.83 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7907128 | 0.83 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7910335 | 0.82 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7910329 | 0.82 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7906993 | 0.81 | FNTA (0.40) | LTB4R2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |