Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.41 |
| ▸ | FNTB | P49356 | 4/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906993 | 0.92 | FNTA (0.40) | FNTAFNTBCASRMTNR1AMTNR1B | |
| SCHEMBL7904963 | 0.89 | SLC6A4 (0.37) | FNTAFNTB | |
| SCHEMBL7904996 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7907250 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7910540 | 0.84 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7905001 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7910543 | 0.84 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7907243 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7906933 | 0.80 | LTB4R2 (0.42) | FFAR1 | |
| SCHEMBL7905224 | 0.75 | FNTA (0.41) | FNTAFNTBCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |