Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904963 | 0.91 | SLC6A4 (0.37) | LTB4R2ADRB1ADRB3IDO1 | |
| SCHEMBL7906993 | 0.88 | FNTA (0.40) | LTB4R2PPARGBRS3FFAR1 | |
| SCHEMBL7910437 | 0.84 | FNTA (0.42) | ADRB1ADRB3BRS3 | |
| SCHEMBL7907128 | 0.84 | FNTA (0.57) | — | |
| SCHEMBL7907130 | 0.84 | FNTA (0.57) | — | |
| SCHEMBL7910335 | 0.84 | FNTA (0.57) | — | |
| SCHEMBL7910329 | 0.84 | FNTA (0.57) | — | |
| SCHEMBL7906347 | 0.82 | FNTA (0.57) | — | |
| SCHEMBL7906339 | 0.82 | FNTA (0.57) | — | |
| SCHEMBL7907018 | 0.80 | FNTA (0.41) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |