Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906935 | 0.90 | FFAR1 (0.44) | FFAR1FFAR4L3MBTL1TDP1MAOB | |
| SCHEMBL7907021 | 0.89 | TDP1 (0.47) | L3MBTL1TDP1ALDH1A1RAB9AFNTA | |
| SCHEMBL7906343 | 0.82 | FNTA (0.62) | FNTAFNTB | |
| SCHEMBL7907129 | 0.81 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL7906995 | 0.80 | TDP1 (0.50) | FFAR1FFAR4L3MBTL1TDP1RAB9A | |
| Lithium Ion SCHEMBL7910333 | 0.79 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7910598 | 0.78 | FNTA (0.43) | FFAR1FFAR4FNTAFNTBSLC6A4 | |
| SCHEMBL7905941 | 0.75 | FNTA (0.44) | FNTAFNTBSLC6A4SLC6A3 | |
| SCHEMBL7907180 | 0.75 | FNTA (0.41) | FFAR1FFAR4L3MBTL1TDP1MAPT | |
| SCHEMBL7904963 | 0.73 | SLC6A4 (0.37) | NPC1ALDH1A1SMN1; SMN2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |