Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.44 |
| ▸ | FNTB | P49356 | 14/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910598 | 0.93 | FNTA (0.43) | FNTAFNTBSLC6A3SLC6A4 | |
| SCHEMBL6624770 | 0.90 | SLC6A3 (0.46) | SLC6A3SLC6A4KMT2ASLC6A2 | |
| SCHEMBL7910206 | 0.90 | FNTA (0.43) | FNTAFNTBSLC6A3SLC6A4 | |
| SCHEMBL7904826 | 0.88 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7903816 | 0.83 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7905477 | 0.83 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL7903834 | 0.83 | FNTA (0.43) | FNTAFNTBKMT2A | |
| SCHEMBL628630 | 0.82 | LOXL2 (0.50) | SLC6A3SLC6A4KMT2ASLC6A2 | |
| SCHEMBL7905904 | 0.82 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL6625716 | 0.81 | SLC6A3 (0.43) | SLC6A3SLC6A4KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |