Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904812 | 0.92 | KDR (0.59) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7904971 | 0.91 | KDR (0.58) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7913398 | 0.81 | KDR (0.56) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7904898 | 0.81 | MAPT (0.59) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7918457 | 0.80 | MEN1 (0.60) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7914896 | 0.79 | MAPT (0.58) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7914954 | 0.79 | MAPT (0.57) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7914621 | 0.78 | KDR (0.49) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7915131 | 0.77 | SHMT2 (0.46) | KDRMEN1KMT2APOLBMAPT | |
| SCHEMBL7905044 | 0.74 | MAPT (0.55) | KDRMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |