Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913398 | 0.94 | KDR (0.56) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7905044 | 0.93 | MAPT (0.55) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7914954 | 0.91 | MAPT (0.57) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7904894 | 0.91 | MAPT (0.62) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7914621 | 0.90 | KDR (0.49) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7914959 | 0.89 | MEN1 (0.50) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7918641 | 0.88 | MAPT (0.45) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7915131 | 0.87 | SHMT2 (0.46) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7904812 | 0.86 | KDR (0.59) | MAPTLMNAKDRMEN1KMT2A | |
| SCHEMBL7918610 | 0.86 | MEN1 (0.56) | MAPTLMNAKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |