Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913364 | 0.89 | KDR (0.58) | KDRMAPTLMNACA9TP53 | |
| SCHEMBL7905464 | 0.87 | MAPT (0.63) | KDRMAPTLMNACA9KMT2A | |
| SCHEMBL8014060 | 0.87 | MAPT (0.66) | KDRMAPTLMNACA9ENPP3 | |
| SCHEMBL7905052 | 0.86 | MAPT (0.58) | KDRMAPTLMNACA9ENPP3 | |
| SCHEMBL7913259 | 0.86 | CA9 (0.63) | KDRMAPTLMNACA9ENPP3 | |
| SCHEMBL788243 | 0.85 | KDR (0.66) | KDRMAPTLMNACA9MEN1 | |
| SCHEMBL7913375 | 0.85 | KDR (0.62) | KDRMAPTLMNACA9TP53 | |
| SCHEMBL7914888 | 0.85 | MAPT (0.64) | KDRMAPTLMNACA9ENPP3 | |
| SCHEMBL7918628 | 0.83 | MAPT (0.81) | KDRMAPTLMNAMEN1KMT2A | |
| SCHEMBL7918387 | 0.83 | MAPT (0.75) | KDRMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |