SCHEMBL7905083

SCHEMBL7905083

Cc1c2ccccc2cc2c(O)cccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.56
HSD17B1 P14061 3/20 0.47
HSD17B2 P37059 3/20 0.47
TRPM4 Q8TD43 1/20 0.47
PLAU P00749 1/20 0.46
NQO2 P16083 1/20 0.45
HSD17B10 Q99714 4/20 0.45
TSHR P16473 3/20 0.45
HPGD P15428 3/20 0.45
CASP1 P29466 2/20 0.45
APP P05067 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
ALOX15 P16050 1/20 0.45
SNCA P37840 1/20 0.45
RECQL P46063 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
HIF1A Q16665 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13763201 0.82 PTPN22 (0.55) CYP1A2HSD17B1HSD17B2TRPM4NQO2
SCHEMBL30196661 0.79 CYP1A2 (0.60) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL2002444 0.79 CYP1A2 (0.60) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL11615489 0.79 ALDH1A1 (0.60) CYP1A2HSD17B10TSHRHPGDCASP1
SCHEMBL9353874 0.79 CYP1A2 (0.58) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL1556427 0.78 ALDH1A1 (0.55) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL29857010 0.78 CYP1A2 (0.62) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL2115683 0.78 CYP1A2 (0.62) CYP1A2HSD17B1HSD17B2TRPM4PLAU
SCHEMBL29360084 0.78 CYP1A2 (0.56) CYP1A2TRPM4NQO2HSD17B10TSHR
SCHEMBL119090 0.78 CYP1A2 (0.56) CYP1A2TRPM4NQO2HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed