SCHEMBL7905100

SCHEMBL7905100

O=C1Sc2ccc3ccccc3c2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 3/20 0.54
DNMT1 P26358 1/20 0.47
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PAX8 Q06710 1/20 0.45
CES1 P23141 2/20 0.44
HPRT1 P00492 2/20 0.43
NSD2 O96028 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
HIF1A Q16665 2/20 0.40
WDR5 P61964 1/20 0.40
CYP1B1 Q16678 1/20 0.40
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436428 0.85 MAPT (0.54) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL30975100 0.84 ALDH1A1 (0.41) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL13935985 0.71 HSD17B10 (0.42) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL10042108 0.70 ALDH1A1 (0.52) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL19230419 0.70 DNMT1 (0.83) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL16144677 0.69 DNMT1 (0.80) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL12236188 0.69 DNMT1 (0.67) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL7122517 0.69 DNMT1 (0.73) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL19230420 0.69 DNMT1 (0.73) MEN1KMT2AMAPTDNMT1ALDH1A1
SCHEMBL30362207 0.69 DNMT1 (0.67) MEN1KMT2AMAPTDNMT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed