Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13936037 | 0.85 | ALDH1A1 (0.41) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL10042108 | 0.76 | ALDH1A1 (0.52) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL13936028 | 0.76 | MEN1 (0.39) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL21436428 | 0.71 | MAPT (0.54) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL7905100 | 0.71 | MEN1 (0.54) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL13936029 | 0.71 | MAPK1 (0.36) | HSD17B10ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL1796145 | 0.67 | ALDH1A1 (0.52) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL887362 | 0.65 | GPR84 (0.50) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL15769977 | 0.64 | TSHR (0.45) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 | |
| SCHEMBL13935969 | 0.64 | GPR84 (0.49) | HSD17B10ALDH1A1TSHRCYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494721-B2 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-7494721-B2 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |