Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TYMS | P04818 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11907457 | 0.91 | LNPEP (0.67) | LNPEPRAB9AGAATYMSCA2 | |
| SCHEMBL7613514 | 0.87 | RAB9A (0.64) | LNPEPRAB9AGAACA2ERAP2 | |
| SCHEMBL7511247 | 0.86 | LNPEP (0.76) | LNPEPRAB9AGAATYMSCA2 | |
| SCHEMBL7511243 | 0.86 | LNPEP (0.76) | LNPEPRAB9AGAATYMSCA2 | |
| SCHEMBL3975596 | 0.85 | LNPEP (0.60) | LNPEPRAB9AGAATYMSCA2 | |
| SCHEMBL3975599 | 0.85 | LNPEP (0.60) | LNPEPRAB9AGAATYMSCA2 | |
| SCHEMBL9088699 | 0.84 | RAB9A (0.71) | LNPEPRAB9AGAACA2ERAP2 | |
| SCHEMBL9088697 | 0.84 | RAB9A (0.71) | LNPEPRAB9AGAACA2ERAP2 | |
| SCHEMBL6093237 | 0.84 | GAA (0.64) | LNPEPRAB9AGAAALDH1A1LMNA | |
| SCHEMBL16846615 | 0.84 | LNPEP (0.59) | LNPEPRAB9AGAATYMSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |