SCHEMBL7905154

SCHEMBL7905154

CC1=C(CCc2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 4/20 0.57
MAPT P10636 3/20 0.54
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
LMNA P02545 2/20 0.54
HTT P42858 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
APAF1 O14727 1/20 0.54
MITF O75030 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TBXAS1 P24557 1/20 0.54
PKM P14618 3/20 0.50
PARK7 Q99497 1/20 0.50
CDC25B P30305 3/20 0.46
CDC25A P30304 2/20 0.46
PGR P06401 1/20 0.46
HTR1A P08908 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
PTGS1 P23219 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5820368 0.90 MAPT (0.58) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL12761936 0.88 TBXAS1 (0.47) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL13675353 0.86 FFAR1 (0.57) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL3047178 0.85 XIAP (0.46) S100A4ALDH1A1TBXAS1PKMPARK7
SCHEMBL7912380 0.83 TBXAS1 (0.69) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL571005 0.81 MAPT (0.53) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL28288758 0.79 MAPT (0.56) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL13649288 0.79 MAPT (0.51) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL13649357 0.79 MAPT (0.59) S100A4MAPTKDM4EALDH1A1LMNA
SCHEMBL5810540 0.78 TBXAS1 (0.62) S100A4MAPTKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed