Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554580 | 0.86 | PARP1 (0.50) | NPC1RAB9ACES2CES1HTT | |
| SCHEMBL4626860 | 0.86 | KDM4E (0.46) | NPC1RAB9ACES2CES1ALDH1A1 | |
| SCHEMBL8321846 | 0.86 | ALDH1A1 (0.46) | NPC1RAB9ACES2CES1MAPT | |
| SCHEMBL1637879 | 0.85 | CA1 (0.46) | NPC1RAB9ACES2CES1HTT | |
| SCHEMBL10397908 | 0.82 | HSD17B2 (0.39) | NPC1RAB9ACES2CES1ALDH1A1 | |
| SCHEMBL7575058 | 0.82 | PLK1 (0.49) | NPC1RAB9AHTTMAPTALDH1A1 | |
| SCHEMBL27470832 | 0.79 | HPGD (0.47) | NPC1RAB9AHTTMAPTALDH1A1 | |
| SCHEMBL27575507 | 0.78 | ESR1 (0.43) | NPC1RAB9ACES2CES1HTT | |
| SCHEMBL4781506 | 0.77 | AKR1C3 (0.41) | RAB9AMAPTNPSR1CYP3A4LMNA | |
| SCHEMBL9651385 | 0.74 | MMP9 (0.48) | NPC1RAB9AHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201102-B1 | BY DISTILLING A LOW BOILING FRACTION FROM A POLYCONDENSATION VESSEL CONTAINING A REACTION PRODUCT OBTAINED BY ACETYLATING RAW MONOMERS WITH ACETIC ANHYDRIDE, CONTROLLING TEMPERATURE OF THE LOW BOILING FRACTION FROM PARTIAL CONDENSER | SUMITOMO CHEMICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-0357079-B1 | Process for producing aromatic polyesters | SUMITOMO CHEMICAL CO (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5015723-A | Process for producing aromatic polyesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0357079-A2 | Process for producing aromatic polyesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |