Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 7/20 | 0.48 |
| ▸ | BCR | P11274 | 6/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915476 | 0.87 | CNR1 (0.45) | MEN1ABL1BCREGFRSRC | |
| SCHEMBL7905958 | 0.86 | PLK1 (0.50) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL7913081 | 0.86 | HDAC3 (0.46) | MEN1ABL1BCRSRCCNR1 | |
| SCHEMBL7346763 | 0.84 | TDO2 (0.50) | KMT2ANPC1PKMKIF11 | |
| SCHEMBL7905830 | 0.82 | SIRT2 (0.48) | MEN1CNR1ALDH1A1HDAC1KMT2A | |
| SCHEMBL7905940 | 0.81 | BRD4 (0.39) | MEN1ABL1BCREGFRSRC | |
| SCHEMBL7916081 | 0.77 | CNR1 (0.47) | ABL1BCRCNR1PRKCACYP2A6 | |
| SCHEMBL7913791 | 0.76 | CXCR2 (0.37) | MEN1ABL1BCREGFRSRC | |
| SCHEMBL14704101 | 0.76 | CYP1A2 (0.56) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL29666524 | 0.76 | CYP1A2 (0.56) | MEN1PSIP1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211220-B1 | ANTITUMOR AGENTS AND ANTICARCIINOGENIC AGENTS | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | claimed |
| US-6211220-B1 | ANTITUMOR AGENTS AND ANTICARCIINOGENIC AGENTS | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |