Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 8/20 | 0.31 |
| ▸ | CA2 | P00918 | 8/20 | 0.31 |
| ▸ | CA9 | Q16790 | 8/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014933 | 0.98 | TSHR (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23014988 | 0.98 | TSHR (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL789504 | 0.94 | KDM4E (0.52) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL791108 | 0.86 | USP2 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL31387771 | 0.80 | KDM4E (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18063438 | 0.78 | CA2 (0.50) | CA1CA2CA9CA12CA3 | |
| SCHEMBL10727268 | 0.77 | TSHR (0.60) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13204670 | 0.76 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9556429 | 0.76 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| Busulfan SCHEMBL4764696 | 0.74 | TSHR (1.00) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921328-B2 | E-selectin antagonists | GLYCOMIMETICS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130331350-A1 | E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2013-12-12 | — | — | US | disclosed |
| WO-2012037034-A1 | E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130331350-A1 | E-SELECTIN ANTAGONISTS | SELE, SELP, SELPLG | KDM4E 3712/4885USP2 4236/4885ALDH1A1 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.