Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903336 | 0.87 | KMT2A (0.45) | KMT2APGRHRH3TP53LMNA | |
| SCHEMBL517193 | 0.87 | PTGES (0.33) | SMN1; SMN2KMT2AMEN1TP53LMNA | |
| SCHEMBL7904520 | 0.80 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1GAAPGR | |
| SCHEMBL517806 | 0.79 | P4HB (0.32) | — | |
| SCHEMBL7606117 | 0.78 | KMT2A (0.44) | SMN1; SMN2KMT2AMEN1PGRALDH1A1 | |
| SCHEMBL7601328 | 0.78 | KMT2A (0.44) | SMN1; SMN2KMT2AMEN1PGRHRH3 | |
| SCHEMBL7601831 | 0.77 | PTGES (0.46) | SMN1; SMN2KMT2AMEN1PGRHRH3 | |
| SCHEMBL13660621 | 0.76 | KMT2A (0.55) | SMN1; SMN2KMT2AMEN1PGRHRH3 | |
| SCHEMBL7899898 | 0.76 | KMT2A (0.45) | SMN1; SMN2KMT2APGRHRH3TP53 | |
| SCHEMBL13660622 | 0.76 | KMT2A (0.52) | SMN1; SMN2KMT2AMEN1GAAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102717-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-16 | — | — | WO | disclosed |