Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906898 | 1.00 | MEN1 (0.40) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL4075297 | 0.94 | MEN1 (0.37) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL14022846 | 0.84 | ALDH1A1 (0.37) | TSHRMAPK1ALDH1A1TP53CYP3A4 | |
| SCHEMBL14022831 | 0.84 | ALDH1A1 (0.37) | TSHRMAPK1ALDH1A1TP53CYP3A4 | |
| SCHEMBL14198257 | 0.83 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL28925083 | 0.83 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL3841379 | 0.82 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL7898330 | 0.82 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL11954753 | 0.82 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL26397994 | 0.82 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750649-B1 | BRANCHED POLYOXAALKYL MACROMOLECULES, PROCESS FOR MAKING THEM AND THEIR USES | BRACCO IMAGING SPA (IT) | 2001-12-19 | — | — | EP | disclosed |