SCHEMBL3841379

SCHEMBL3841379

OCCOCC(CO)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
MAPK1 P28482 2/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 4/20 0.41
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25885638 0.94 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL15463146 0.94 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL28925083 0.89 MEN1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14198257 0.89 MEN1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL4075297 0.88 MEN1 (0.37) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL75556 0.88 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL17173618 0.87 TSHR (0.43) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14997583 0.85 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14997582 0.85 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL11287412 0.85 TSHR (0.41) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047356-B Method for refining eucommia ulmoides crude glue solution 山东贝隆杜仲生物工程有限公司 2020-06-16 CN claimed
WO-2015021625-A1 COMPOSITION COMPRISING PASTY COMPOUNDS AND ORGANIC UV FILTER L'OREAL (FR) 2015-02-19 WO claimed
WO-2014163768-A1 NEOPOLYOLS SUITABLE FOR CRYSTAL GROWTH MODIFICATION IN THE BAYER PROCESS ECOLAB USA INC. (US) 2014-10-09 WO claimed
US-20140271416-A1 NEOPOLYOLS SUITABLE FOR CRYSTAL GROWTH MODIFICATION IN THE BAYER PROCESS ECOLAB USA INC. (US) 2014-09-18 US claimed
US-20060134057-A1 Cosmetic composition comprising a polyol ether and an ester L'OREAL S.A. (FR) 2006-06-22 US claimed
US-20060120989-A1 Cosmetic composition comprising at least one polyol ether and at least one pasty substance L'OREAL S.A. (FR) 2006-06-08 US claimed
US-4243500-A ACRYLATE ESTER, TACKIFYING RESIN, NONCRYSTALLINE ELASTOMER INTERNATIONAL COATINGS, CO., INC. (US) 1981-01-06 US claimed
CN-109152714-B Cosmetic composition comprising a water-soluble dye 欧莱雅 2024-07-05 CN disclosed
CN-111344044-B Emulsion comprising anionic acrylic copolymer and lipophilic polymer 莱雅公司 2024-03-22 CN disclosed
CN-117396186-A Anhydrous composition for caring for and/or making up keratin materials 莱雅公司 2024-01-12 CN disclosed
CN-117255676-A Solid anhydrous composition for caring for and/or making up keratin materials 莱雅公司 2023-12-19 CN disclosed
CN-112891236-B Cosmetic solid composition 莱雅公司 2023-10-13 CN disclosed
CN-111356433-B Composition comprising a fatty phase, a lipophilic polymer and a volatile hydrocarbon-based oil 莱雅公司 2023-07-25 CN disclosed
EP-0492184-B1 Chlorinated ethylene copolymer latex DU PONT (US) 1995-09-06 EP disclosed
US-5182322-A CHLORINATED ETHYLENE COPOLYMER LATEX E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-26 US disclosed
EP-0492184-A2 Chlorinated ethylene copolymer latex E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-01 EP disclosed
US-4311759-A ACRYLATE CURED WITH ELASTOMERIC BLOCK POLYMER, TACKIFIER RESIN INTERNATIONAL COATINGS CO., INC. (US) 1982-01-19 US disclosed
US-4243500-A ACRYLATE ESTER, TACKIFYING RESIN, NONCRYSTALLINE ELASTOMER INTERNATIONAL COATINGS, CO., INC. (US) 1981-01-06 US disclosed
US-3981851-A TACKIFIERS, AMINOSILANES DOW CORNING CORPORATION (US) 1976-09-21 US disclosed
US-3955036-A TACKIFIERS, ORGANOSILICON COMPOUNDS DOW CORNING CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060120989-A1 Cosmetic composition comprising at least one polyol ether and at least one pasty substance KRT18, CUTA, DSG1 TSHR 3799/4885MAPK1 1511/4885MEN1 1034/4885
US-20060134057-A1 Cosmetic composition comprising a polyol ether and an ester CUTA, KRT18, FABP4 TSHR 2607/4885MAPK1 2182/4885MEN1 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.