SCHEMBL7905899

SCHEMBL7905899

C=CCCC(C)(O)C(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
CES1 P23141 2/20 0.40
AKT1 P31749 1/20 0.40
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
MAPT P10636 1/20 0.37
ELANE P08246 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 2/20 0.36
HTT P42858 1/20 0.36
TBXAS1 P24557 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292363 0.84 CES1 (0.50) SRCCES1ALDH1A1TSHRHPGD
SCHEMBL11086781 0.83 MAPT (0.50) SRCHSP90AA1CES1AKT1ALDH1A1
SCHEMBL9617688 0.79 SRC (0.46) SRCCES1ALDH1A1TSHRLMNA
SCHEMBL8759046 0.78 SRC (0.48) SRCCES1ALDH1A1TSHRHPGD
SCHEMBL29107368 0.78 TBXAS1 (0.40) SRCCES1ALDH1A1LMNAMAPT
SCHEMBL195379 0.76 CES1 (0.50) SRCCES1ALDH1A1TSHRLMNA
SCHEMBL29064653 0.76 CES1 (0.43) SRCHSP90AA1HSP90AB1CES1ALDH1A1
SCHEMBL6698046 0.76 CES1 (0.47) SRCCES1LMNATDP1
SCHEMBL6059309 0.76 TET2 (0.45) HSP90AA1HSP90AB1ALDH1A1TSHRLMNA
SCHEMBL7910874 0.75 CES1 (0.37) SRCCES1AKT1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US claimed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US claimed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP claimed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US disclosed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US disclosed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP disclosed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO disclosed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US disclosed
US-20010007880-A1 Material based on crosslinked silicone polymer comprising an immobilized photoinitiator, process for the preparation thereof, hydrophilic polymeric product obtained from this material and process for the preparation thereof, and novel photoinitiators ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2001-07-12 US disclosed
US-6197842-B1 CONTACT LENSES ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2001-03-06 US disclosed