Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.74 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816128 | 0.98 | MITF (0.71) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5992122 | 0.87 | MITF (0.74) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6215102 | 0.86 | KDM4E (0.68) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5992289 | 0.85 | ALDH1A1 (1.00) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12679652 | 0.85 | MITF (0.72) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5995175 | 0.85 | MITF (0.72) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18569422 | 0.85 | KDM4E (0.72) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12679658 | 0.84 | MEN1 (0.67) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12679654 | 0.84 | MEN1 (0.67) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11407980 | 0.84 | MEN1 (0.65) | MITFALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207852-B1 | THERAPY FOR INCONTINENCE; CROHN'S DISEASE; MUSCLE RELAXANTS | BRIDGE PHARMA, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-0915826-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0915826-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | Bridge Pharma, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998000390-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| US-3954827-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |