Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912709 | 0.83 | C5AR1 (0.44) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5500435 | 0.81 | HRH1 (0.36) | ALDH1A1RECQLACHEMCHR1 | |
| SCHEMBL297165 | 0.78 | ACHE (0.50) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11763224 | 0.77 | ACHE (0.39) | ALDH1A1ACHEMCHR1ESR1ESR2 | |
| SCHEMBL7909268 | 0.77 | ACHE (0.54) | ALDH1A1ACHEESR1ESR2PSMB1 | |
| SCHEMBL7906139 | 0.77 | ACHE (0.54) | ALDH1A1ACHEESR1ESR2PSMB1 | |
| SCHEMBL5503980 | 0.77 | ACHE (0.54) | ALDH1A1ACHEESR1ESR2PSMB1 | |
| SCHEMBL7907579 | 0.75 | ACHE (0.51) | ALDH1A1ACHEESR1ESR2PSMB1 | |
| SCHEMBL382809 | 0.75 | PDK2 (0.44) | ALDH1A1RECQLMCHR1ESR1ESR2 | |
| SCHEMBL5493886 | 0.75 | ACHE (0.40) | ALDH1A1ACHEMCHR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |