Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579992 | 0.91 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDESR1 | |
| Acrylic Acid Methyl Ester SCHEMBL7557563 | 0.84 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL26628042 | 0.83 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| Acrylic Acid Ethyl Ester SCHEMBL11276113 | 0.82 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGD | |
| Vinylsulfonic Acid SCHEMBL9630111 | 0.82 | TSHR (0.35) | TSHRPOLBAPEX1HTTTDP1 | |
| Acrylic Acid SCHEMBL11783796 | 0.80 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| Methacrylic Acid SCHEMBL9709007 | 0.80 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL264350 | 0.80 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL2196152 | 0.79 | TSHR (0.51) | TSHRALDH1A1CYP3A4HPGDHTT | |
| Acrylic Acid Ethyl Ester SCHEMBL7580730 | 0.79 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197289-B1 | Removal of biologically active agents | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6146771-A | Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| EP-1021216-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | Terumo Cardiovascular Systems Corporation (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-0994745-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | Terumo Cardiovascular Systems Corporation (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001195-A1 | REMOVAL OF BIOLOGICALLY ACTIVE AGENTS | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001167-A1 | PROCESS FOR MODIFIYING SURFACES USING THE REACTION PRODUCT OF A WATER-INSOLUBLE POLYMER AND A POLYALKLENE IMINE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |