Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988829 | 0.87 | ITGB3 (0.59) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL29780735 | 0.84 | ALDH1A1 (0.64) | ITGB3ITGA2BMAPTALDH1A1KDM4E | |
| SCHEMBL7742078 | 0.83 | HDAC8 (0.48) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL5147726 | 0.83 | ITGB1 (0.44) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL13913372 | 0.82 | ITGB1 (0.59) | ITGB1 | |
| SCHEMBL4316611 | 0.82 | ITGB1 (0.59) | ITGB1 | |
| SCHEMBL7375970 | 0.81 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7416608 | 0.81 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7375972 | 0.79 | ITGB3 (0.58) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL20045974 | 0.79 | PPARG (0.53) | ITGB3ITGA2BMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |