Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184692 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1555585 | 0.68 | CCNA2 (0.46) | HTTALDH1A1MEN1KMT2ASMPD3 | |
| SCHEMBL14813505 | 0.67 | HTT (0.44) | HTTALDH1A1MEN1KMT2ASMPD3 | |
| SCHEMBL31465821 | 0.67 | RET (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28667202 | 0.66 | GPR119 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17310093 | 0.66 | SUV39H2 (0.49) | ALDH1A1SLC2A1MEN1KMT2ATLR9 | |
| SCHEMBL28962607 | 0.66 | CKS1B (0.47) | ALDH1A1SLC2A1TLR9 | |
| SCHEMBL2366187 | 0.65 | GBA1 (0.47) | ALDH1A1MEN1KMT2ATLR9SMPD3 | |
| SCHEMBL5683408 | 0.65 | ABCB1 (0.60) | ALDH1A1MEN1KMT2A | |
| SCHEMBL18653361 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062559-A1 | SUBSTITUTED PYRAZOLOQUINOLINES AND DERIVATIVES THEREOF | SCHERING CORPORATION (US) | 2010-06-03 | — | — | WO | disclosed |