Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | POLA1 | P09884 | 2/20 | 0.55 |
| ▸ | POLD1 | P28340 | 1/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.44 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22110712 | 1.00 | POLB (0.55) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL7906710 | 1.00 | POLB (0.55) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL23622527 | 0.98 | POLB (0.52) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL19389391 | 0.92 | POLB (0.49) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL22508622 | 0.91 | POLB (0.48) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL21345344 | 0.90 | POLA1 (0.49) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL21345704 | 0.90 | P2RY2 (0.46) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL15713242 | 0.90 | TK1 (0.53) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL3031874 | 0.89 | POLB (0.68) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL77582 | 0.89 | POLB (0.68) | POLBPOLA1POLD1P2RY6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021137913-A2 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
| WO-2019173602-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2019-09-12 | — | — | WO | disclosed |
| US-6194141-B1 | DETECTING MODULATOR OF VIRAL PROPAGATION; INCUBATE VIRAL NUCLEOTIDE SEQUENCE MIXTURE WITH METALS, INCUBATE SECOND MIXTURE WITH MODULATOR, CALIBRATE AND COMPARE AMOUNT OF URIDINE INCORPORATED INTO TRANSCRIPTS IN BOTH MIXTURES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-02-27 | — | — | US | disclosed |