SCHEMBL7906733

SCHEMBL7906733

COCNc1ncnc(NCOC)n1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
HTR7 P34969 1/20 0.36
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
KCNH3 Q9ULD8 3/20 0.33
EPHB4 P54760 1/20 0.33
IGF1R P08069 1/20 0.33
LDHA P00338 1/20 0.32
MAPT P10636 1/20 0.31
PTK2 Q05397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8865102 0.86 SMN1; SMN2 (0.53) SMN1; SMN2LMNAHTTMAPT
SCHEMBL16317974 0.84 HTR7 (0.40) SMN1; SMN2HTR7
SCHEMBL122723 0.83 CYP1A2 (0.39) LMNAHTTKCNH3
SCHEMBL3828795 0.82 HSP90AA1 (0.35) LMNA
SCHEMBL14773221 0.76
SCHEMBL16641259 0.74 LMNA (0.54) LMNAHTTMAPT
SCHEMBL17549912 0.74 CA1 (0.37) LMNAKCNH3
SCHEMBL18752060 0.74 LMNA (0.54) LMNAHTTMAPT
SCHEMBL17371045 0.74 CA1 (0.37) LMNAKCNH3
SCHEMBL5954721 0.74 GAA (0.43) HTR7LMNAKCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6221989-B1 CRESOL-FORMALDEHYDE RESIN CONTAINING TRIAZINE GROUPS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-04-24 US disclosed