Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178607 | 0.87 | TSHR (0.36) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL31127935 | 0.87 | TSHR (0.36) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL17891351 | 0.87 | TSHR (0.36) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL1930958 | 0.87 | TSHR (0.36) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL301354 | 0.85 | TSHR (0.37) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL3189947 | 0.84 | TSHR (0.38) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL9871556 | 0.80 | TSHR (0.41) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL14066255 | 0.78 | TSHR (0.42) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL13198515 | 0.78 | TSHR (0.35) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL7906779 | 0.77 | TSHR (0.44) | TSHRALDH1A1HPGDTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221988-B1 | NONAQUEOUS PROTECTIVE COATINGS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 2001-04-24 | — | — | US | disclosed |