Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 6/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479952 | 0.82 | KCNE1 (0.44) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL7471445 | 0.81 | KCNE1 (0.42) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL8477181 | 0.79 | KCNE1 (0.46) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL7464771 | 0.79 | KCNE1 (0.42) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL8477178 | 0.76 | KCNE1 (0.46) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL8476683 | 0.75 | KCNE1 (0.46) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL6601925 | 0.74 | KCNE1 (0.44) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL8477143 | 0.74 | KCNE1 (0.49) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL8306392 | 0.74 | KCNE1 (0.43) | MAPTALDH1A1HTTTAAR1KCNE1 | |
| SCHEMBL7910522 | 0.74 | KCNE1 (0.43) | MAPTALDH1A1HTTTAAR1KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |