Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 7/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471445 | 0.88 | KCNE1 (0.42) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7464771 | 0.88 | KCNE1 (0.42) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8477143 | 0.87 | KCNE1 (0.49) | KCNE1KCNQ1ALDH1A1KDM4EHPGD | |
| SCHEMBL8479952 | 0.86 | KCNE1 (0.44) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8477178 | 0.86 | KCNE1 (0.46) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8476715 | 0.81 | KCNE1 (0.45) | KCNE1KCNQ1ALDH1A1KDM4EHPGD | |
| SCHEMBL7906983 | 0.79 | MAPT (0.39) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8476683 | 0.79 | KCNE1 (0.46) | KCNE1KCNQ1ALDH1A1GAAMAPT | |
| SCHEMBL8476706 | 0.78 | KCNE1 (0.47) | KCNE1KCNQ1ALDH1A1KDM4EHPGD | |
| SCHEMBL7469113 | 0.78 | ALDH1A1 (0.46) | KCNE1KCNQ1MTNR1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |