Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrene SCHEMBL7907124 | 1.00 | RELA (0.60) | RELAALDH1A1HPGDCYP3A4TSHR | |
| Pyrene SCHEMBL27498377 | 0.86 | ALDH1A1 (0.48) | RELAALDH1A1HPGDCYP3A4TSHR | |
| Pyrene SCHEMBL27594669 | 0.86 | CYP1B1 (0.48) | RELAALDH1A1HPGDCYP3A4TSHR | |
| (Z)-1,2-Diphenylethene SCHEMBL27485869 | 0.85 | ALDH1A1 (0.54) | RELAALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL131580 | 0.84 | RELA (0.46) | RELAALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL31550572 | 0.84 | RELA (0.46) | RELAALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL131581 | 0.84 | RELA (0.46) | RELAALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL31236793 | 0.81 | CYP1A2 (0.50) | RELAALDH1A1HPGDCYP1A2HSD17B10 | |
| Pyrene SCHEMBL9716948 | 0.80 | ALDH1A1 (0.67) | RELAALDH1A1HPGDCYP3A4TSHR | |
| Pyrene SCHEMBL4936826 | 0.80 | ALDH1A1 (0.67) | RELAALDH1A1HPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218108-B1 | NUCLEOSIDE DERIVATIVE COMPRISING PYRENE, ANTHRACENE, PHENANTHRENE, STILBENE, TETRACENE OR PENTACENE JOINED TO THE C-1 ATOM OF A RIBOSE OR DEOXYRIBOSE SUGAR; PROBES FOR FLUORESCENT IN SITU HYBRIDIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2001-04-17 | — | — | US | disclosed |
| US-6140480-A | ADDUCT OF HOFFER'S CHLOROSUGAR COMPRISING AN ORGANOCADMIUM OR ORGANOZINC DERIVATIVE OF PYRENE, ANTHRACENE, PHENANTHRENE, STILBENE, TETRACENE, OR PENTACENE COUPLED TO THE C1 POSITION; FLUORESCENT PROBES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |