Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78061 | 0.94 | ACHE (0.51) | TRPV1ACHEBCHEALDH1A1TRPA1 | |
| SCHEMBL80101 | 0.81 | MEN1 (0.66) | TRPV1ACHEMEN1KMT2ATRPA1 | |
| SCHEMBL12043586 | 0.81 | ACHE (0.55) | TRPV1ACHEBCHEALDH1A1CHRM2 | |
| SCHEMBL11055180 | 0.80 | FAAH (0.55) | ACHEBCHEKDM4EMAPT | |
| SCHEMBL77171 | 0.79 | ACHE (0.47) | TRPV1ACHEBCHEALDH1A1CHRM2 | |
| SCHEMBL77554 | 0.79 | ACHE (0.47) | TRPV1ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL27836777 | 0.79 | KMT2A (0.62) | ACHEBCHEALDH1A1MEN1KMT2A | |
| SCHEMBL14439401 | 0.79 | CYP3A4 (0.50) | TRPV1ACHEMEN1KMT2ATRPA1 | |
| Phenyl Methylcarbamate SCHEMBL28014399 | 0.79 | CYP1A2 (0.53) | ACHEBCHEALDH1A1MEN1KMT2A | |
| SCHEMBL10815679 | 0.79 | ACHE (0.61) | ACHEBCHEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129428-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |