Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.40 |
| ▸ | MC5R | P33032 | 18/20 | 0.40 |
| ▸ | MC3R | P41968 | 11/20 | 0.40 |
| ▸ | MC1R | Q01726 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378853 | 0.81 | KIT (0.46) | MC4RMC5RMC3RMC1R | |
| SCHEMBL7912435 | 0.80 | KIT (0.45) | MC4RMC5RMC3RMC1R | |
| SCHEMBL7899560 | 0.73 | HTT (0.43) | MC4RMC5RMC3RMC1R | |
| SCHEMBL7902076 | 0.73 | HSD11B1 (0.34) | — | |
| SCHEMBL13092275 | 0.72 | GRM5 (0.45) | — | |
| SCHEMBL7908887 | 0.72 | GRM5 (0.45) | — | |
| SCHEMBL7907548 | 0.72 | NPC1 (0.42) | MC4RMC5RMC3RMC1R | |
| SCHEMBL378826 | 0.72 | TACR3 (0.41) | — | |
| SCHEMBL378763 | 0.71 | TACR3 (0.40) | MC4RMC5RMC3RMC1R | |
| SCHEMBL7908417 | 0.70 | KIT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106081-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-23 | — | — | WO | disclosed |